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Immune

Thymosin Alpha-1

Also called Thymalfasin, Zadaxin, Tα1

InjectableEvidence A2x per week
Half-life
2hours
Typical vial
1.6mg
Research amounts
1.6–1.6mg

per administration

Common schedule
2x per week
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

Licensed as a medicine in roughly 35 countries, though never the US.

Work out your draw

These numbers are a starting point — change any of them.

3 mL cartridge · 200 units loaded200units dialled
Concentration
0.8mg/mL
Volume per draw
2mL
Units to dial
200
Doses per cartridge
1

This is 200 units, past the 60-unit dial. Splitting it across administrations, or using less water to raise the concentration, brings it back into range.

Dial range varies by pen; 1–60 units is the common configuration.

Vial label

Copy this into your label printer.

Published research contexts for Thymosin Alpha-1 describe 1.61.6 mg per administration. Descriptive only, not a recommendation.

Roughly 2 hours in plasma.

An immune-modulating peptide licensed as a medicine in roughly 35 countries but never in the US. Human dosing was subcutaneous, so a schedule table is shown; the amount matches the chronic hepatitis B study and the Zadaxin label.

Dosing schedule

How Thymosin Alpha-1 is commonly stepped up, for reference only.

These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.

PhaseAmountFrequencyRoute
Reported scheduleThe amount and spacing given to trial participants in the chronic hepatitis B study and carried on the Zadaxin label.1.6 mgTwice weeklySubQ

Modelled level — 2x per week

1× is the peak after a single dose.

Steady-state peak
1.00× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
10hours

About five half-lives

Administrations
2/ week

Where these numbers come from

  • Andreone P et al., Hepatology 1996A placebo-controlled study of chronic hepatitis B gave thymosin alpha-1 1.6 mg subcutaneously twice weekly to trial participants over about six months.
  • Zadaxin (thymalfasin) product labelLicensed as a medicine in roughly 35 countries; the label lists 1.6 mg subcutaneously twice weekly.

Next steps