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Recovery

Teduglutide

Also called Gattex, Revestive, ALX-0600

InjectableEvidence AEvery day
Half-life
2hours
Typical vial
5mg
Research amounts
3–4mg

per administration

Common schedule
Every day
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

Licensed as a medicine in the US and EU.

Work out your draw

These numbers are a starting point — change any of them.

3 mL cartridge · 300 units loaded180units dialled
Concentration
1.67mg/mL
Volume per draw
1.8mL
Units to dial
180
Doses per cartridge
1

This is 180 units, past the 60-unit dial. Splitting it across administrations, or using less water to raise the concentration, brings it back into range.

Dial range varies by pen; 1–60 units is the common configuration.

Vial label

Copy this into your label printer.

Published research contexts for Teduglutide describe 34 mg per administration. Descriptive only, not a recommendation.

Dosing schedule

How Teduglutide is commonly stepped up, for reference only.

These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.

PhaseAmountFrequencyRoute
Reported daily doseThe licensed once-daily amount; the dose-finding study ran 0.03–0.15 mg/kg for 21 days.0.05 mg/kg (about 3–4 mg for a 60–80 kg adult)Once dailySubQ

Modelled level — every day

1× is the peak after a single dose.

Steady-state peak
1.00× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
10hours

About five half-lives

Administrations
7/ week

Where these numbers come from

  • Jeppesen PB et al., Gut 2005;54:1224Subcutaneous teduglutide (ALX-0600) at 0.03–0.15 mg/kg daily for 21 days assessed for intestinal absorption in short-bowel syndrome.

Next steps

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