Metabolic
PYY3-36
Also called Peptide YY(3-36)
per administration
A human trial worked out how much to take and how often, so a dosing schedule is shown.
The human evidence for PYY3-36 used the intravenous route. The draw worked out here assumes a subcutaneous injection, so the amount is not a direct read-across.
Work out your draw
These numbers are a starting point — change any of them.
- Concentration
- 1.67mg/mL
- Volume per draw
- 0.01mL
- Units to dial
- 1
- Doses per cartridge
- 300
Requested 0.006 mL
Requested 0.6
0.6 units is between clicks. The nearest setting is 1, which delivers 16.7 mcg instead of 10 mcg.
Vial label
Copy this into your label printer.
Published research contexts for PYY3-36 describe 10–50 mcg per administration. Descriptive only, not a recommendation.
Roughly 8–10 minutes; the decay chart is largely illustrative here.
A gut hormone and Y2 receptor agonist studied for reduced food intake. The human evidence used intravenous infusion (Batterham, Nature 2002 and NEJM 2003); no subcutaneous schedule is established, so no schedule table is shown.
Modelled level — every day
1× is the peak after a single dose.
- Steady-state peak
- 0.98× single dose
- Time to steady state
- 1hours
- Administrations
- 7/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- Batterham RL et al., Nature 2002;418:650Intravenous PYY3-36 infusion reduced food intake in a controlled study of volunteers.
- Batterham RL et al., NEJM 2003;349:941Intravenous infusion lowered energy intake across lean and obese subjects; the route is infusion, not subcutaneous.