Cognitive

P021

Also called P21

InjectableEvidence CEvery day

Half-life

6hours

Typical vial

10mg

Research amounts

1–5mg

per administration

Common schedule

Every day

Animal or lab only

Only animal or lab studies exist — no human study has set an amount.

Work out your draw

These numbers are a starting point — change any of them.

Amount in the vialmgBacteriostatic water you addmLAmount per drawmgAmount unitDevice

Concentration: 3.33mg/mL
Volume per draw: 0.3mL
Units to dial: 30
Doses per cartridge: 10

Vial label

Copy this into your label printer.

Label nameDate you mixed itFormatFor 24 mm tape, or 1" x 2 1/8" die-cut stock such as Dymo 30336.

P021  3.33 mg/mL
30 units = 1 mg
Recon 2026-09-17

Published research contexts for P021 describe 1–5 mg per administration. Descriptive only, not a recommendation.

No human pharmacokinetics; the figure is an order-of-magnitude placeholder from rodent work where it is reported to be orally active.

Evidence is preclinical: a ciliary neurotrophic factor (CNTF)–derived, adamantylated peptidomimetic studied in rodent neurogenesis and tau models and reported to be orally active. No human dose-ranging data exists and no amount or schedule is established, so the figures here are nominal and no schedule table is shown.

Modelled level — every day

1× is the peak after a single dose.

Steady-state peak: 1.07× single dose
Time to steady state: 30hours
Administrations: 7/ week

Where these numbers come from

P021 CNTF-peptidomimetic literature (Iqbal/Kazim)A CNTF-derived compound reported to raise neurogenesis and lower tau pathology in mouse models; no human dosing literature.

Next steps

Plan P021 alongside other compounds Work out cost per draw