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Octreotide

Also called Sandostatin, SMS 201-995

InjectableEvidence ATwice a day
Half-life
1.7hours
Typical vial
1 / 5mg
Research amounts
50–500mcg

per administration

Common schedule
Twice a day
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

Licensed as a medicine in the US and EU.

Work out your draw

These numbers are a starting point — change any of them.

3 mL cartridge · 300 units loaded15units dialled
Concentration
0.33mg/mL
Volume per draw
0.15mL
Units to dial
15
Doses per cartridge
20

Vial label

Copy this into your label printer.

Published research contexts for Octreotide describe 50500 mcg per administration. Descriptive only, not a recommendation.

About 1.7 h for the immediate-release form; the monthly depot is a separate formulation with its own kinetics.

Octreotide (SMS 201-995), a synthetic somatostatin analog, licensed as a medicine in the US and EU. The immediate-release form is given subcutaneously about three times a day at 50–500 mcg; a separate long-acting depot is injected intramuscularly once a month and its figures do not carry over to this curve. The nearest standing frequency in the model is twice daily, so the three-times-daily schedule is stated in the table. Kvols (NEJM 1986) reported subcutaneous dosing in carcinoid syndrome research.

Dosing schedule

How Octreotide is commonly stepped up, for reference only.

These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.

PhaseAmountFrequencyRoute
Immediate-releaseThe short-acting form; a monthly intramuscular depot is a separate formulation.50–500 mcgThree times dailySubQ

Modelled level — twice a day

1× is the peak after a single dose.

Steady-state peak
1.00× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
9hours

About five half-lives

Administrations
14/ week

Where these numbers come from

  • Kvols LK et al., NEJM 1986;315:663A long-acting somatostatin analogue evaluated in malignant carcinoid syndrome; subcutaneous dosing measured symptom scores and circulating hormone markers.

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