Metabolic
Metreleptin
Also called Myalept
per administration
A human trial worked out how much to take and how often, so a dosing schedule is shown.
Licensed as a medicine in the US and EU.
Work out your draw
These numbers are a starting point — change any of them.
- Concentration
- 3.77mg/mL
- Volume per draw
- 0.66mL
- Units to dial
- 66
- Doses per cartridge
- 4
Requested 0.664 mL
Requested 66.37
This is 66.4 units, past the 60-unit dial. Splitting it across administrations, or using less water to raise the concentration, brings it back into range.
66.37 units is between clicks. The nearest setting is 66, which delivers 2.486 mg instead of 2.5 mg.
Dial range varies by pen; 1–60 units is the common configuration.
Vial label
Copy this into your label printer.
Published research contexts for Metreleptin describe 2.5–10 mg per administration. Descriptive only, not a recommendation.
Roughly 4 hours in plasma, consistent with once-daily administration.
Dosing schedule
How Metreleptin is commonly stepped up, for reference only.
These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.
| Phase | Amount | Frequency | Route |
|---|---|---|---|
| MaintenanceA recombinant leptin analog dosed by body weight; the licensed label titrates within this range. | 2.5–10 mg (weight-based) | Once daily | SubQ |
Modelled level — every day
1× is the peak after a single dose.
- Steady-state peak
- 1.02× single dose
- Time to steady state
- 20hours
- Administrations
- 7/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- Metreleptin (Myalept / Myalepta) label and lipodystrophy studiesLicensed leptin analog given once daily by body weight in generalized and partial lipodystrophy research.