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Sexual and reproductive health

Melanotan-2 (MT-2)

Also called MT-II, MT-2

InjectableEvidence A5 days on, 2 off
Half-life
1.5hours
Typical vial
10mg
Research amounts
0.7–2.1mg

per administration

Common schedule
5 days on, 2 off
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

Work out your draw

These numbers are a starting point — change any of them.

3 mL cartridge · 300 units loaded21units dialled
Concentration
3.33mg/mL
Volume per draw
0.21mL
Units to dial
21
Doses per cartridge
14

Vial label

Copy this into your label printer.

Published research contexts for Melanotan-2 (MT-2) describe 0.72.1 mg per administration. Descriptive only, not a recommendation.

Roughly 1–2 hours, but poorly characterized; published estimates vary.

The one human dosing source is a three-subject 1996 safety pilot (Dorr), not a dose-ranging trial, so the tier-A grade and the schedule below both rest on an n=3 sample and should be read as provisional.

Dosing schedule

How Melanotan-2 (MT-2) is commonly stepped up, for reference only.

These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.

PhaseAmountFrequencyRoute
Reported rangeA melanocortin agonist. These amounts come from a three-subject 1996 pilot; the sample is far too small to fix a schedule.0.01–0.03 mg/kg (about 0.7–2.1 mg for a 70 kg adult)Once daily, Monday–FridaySubQ

Modelled level — 5 days on, 2 off

1× is the peak after a single dose.

Steady-state peak
1.00× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
8hours

About five half-lives

Administrations
5/ week

Where these numbers come from

  • Dorr RT et al., Life Sci 1996;58:1777A three-subject safety pilot of melanotan-II given subcutaneously at 0.01–0.03 mg/kg on a weekday schedule.

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