Skip to content

Sexual and reproductive health

Leuprolide

Also called Lupron, Leuprorelin

InjectableEvidence AEvery day
Half-life
3hours
Typical vial
1 / 5mg
Research amounts
1–7.5mg

per administration

Common schedule
Every day
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

Licensed as a medicine in the US and EU.

Work out your draw

These numbers are a starting point — change any of them.

3 mL cartridge · 300 units loaded300units dialled
Concentration
0.33mg/mL
Volume per draw
3mL
Units to dial
300
Doses per cartridge
1

This is 300 units, past the 60-unit dial. Splitting it across administrations, or using less water to raise the concentration, brings it back into range.

Dial range varies by pen; 1–60 units is the common configuration.

Vial label

Copy this into your label printer.

Published research contexts for Leuprolide describe 17.5 mg per administration. Descriptive only, not a recommendation.

About 3 hours for the immediate-release peptide; the licensed depot releases over one to six months, with different kinetics.

A gonadotropin-releasing hormone agonist, licensed as a medicine as both a 1 mg daily subcutaneous form and a long-acting depot; because the depot dominates use and no dose-ranging escalation applies, no schedule table is shown.

Modelled level — every day

1× is the peak after a single dose.

Steady-state peak
1.00× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
15hours

About five half-lives

Administrations
7/ week

Where these numbers come from

  • Leuprolide (Lupron) product literatureA licensed GnRH agonist given as 1 mg daily subcutaneously or as a monthly-to-six-monthly depot.

Next steps

Others in sexual and reproductive health