Skip to content

Longevity

Elamipretide

Also called SS-31, Forzinity, MTP-131, Bendavia

InjectableEvidence AEvery day
Half-life
2hours
Typical vial
40mg
Research amounts
40–40mg

per administration

Common schedule
Every day
Tested in people

A human trial worked out how much to take and how often, so a dosing schedule is shown.

Licensed as a medicine in the US.

Work out your draw

These numbers are a starting point — change any of them.

3 mL cartridge · 200 units loaded200units dialled
Concentration
20mg/mL
Volume per draw
2mL
Units to dial
200
Doses per cartridge
1

This is 200 units, past the 60-unit dial. Splitting it across administrations, or using less water to raise the concentration, brings it back into range.

Dial range varies by pen; 1–60 units is the common configuration.

Vial label

Copy this into your label printer.

Published research contexts for Elamipretide describe 4040 mg per administration. Descriptive only, not a recommendation.

A mitochondrial-targeted (Szeto–Schiller) peptide that binds cardiolipin on the inner mitochondrial membrane; studied at 40 mg daily subcutaneously and licensed as a medicine in the US in 2025 under the brand Forzinity.

Dosing schedule

How Elamipretide is commonly stepped up, for reference only.

These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.

PhaseAmountFrequencyRoute
MaintenanceThe single daily amount used in the TAZPOWER trial and carried onto the Forzinity label; no escalation was reported.40 mgOnce dailySubQ

Modelled level — every day

1× is the peak after a single dose.

Steady-state peak
1.00× single dose

Read off the modelled curve, not an even-interval formula

Time to steady state
10hours

About five half-lives

Administrations
7/ week

Where these numbers come from

  • TAZPOWER (Reid Thompson W et al., Genetics in Medicine 2021)Randomized crossover then open-label extension of elamipretide 40 mg/day subcutaneously in Barth syndrome trial participants.
  • Forzinity (elamipretide) product labelBrand approved in the US in 2025; 40 mg once-daily subcutaneous dosing.

Next steps

Others in longevity