Metabolic
Dulaglutide
Also called Trulicity
per administration
A human trial worked out how much to take and how often, so a dosing schedule is shown.
Licensed as a medicine in the US and EU.
Work out your draw
These numbers are a starting point — change any of them.
- Concentration
- 1mg/mL
- Volume per draw
- 0.75mL
- Units to dial
- 75
- Doses per cartridge
- 4
This is 75 units, past the 60-unit dial. Splitting it across administrations, or using less water to raise the concentration, brings it back into range.
Dial range varies by pen; 1–60 units is the common configuration.
Vial label
Copy this into your label printer.
Published research contexts for Dulaglutide describe 0.75–4.5 mg per administration. Descriptive only, not a recommendation.
About 4.7 days. Built as a GLP-1 analog fused to a modified IgG4 Fc fragment, which is what stretches elimination to several days and supports once-weekly dosing.
Dosing schedule
How Dulaglutide is commonly stepped up, for reference only.
These are commonly-discussed research protocols shared for educational reference. This is not medical advice and is not a substitute for guidance from a qualified professional.
| Phase | Amount | Frequency | Route |
|---|---|---|---|
| Weeks 1–4Starting step. | 0.75 mg | Once weekly | SubQ |
| Weeks 5+ | 1.5 mg | Once weekly | SubQ |
| After ≥4 weeks | 3 mg | Once weekly | SubQ |
| After ≥4 more weeksHighest step in AWARD-11; step up no sooner than every 4 weeks. | 4.5 mg | Once weekly | SubQ |
Modelled level — once a week
1× is the peak after a single dose.
- Steady-state peak
- 1.49× single dose
- Time to steady state
- 23.5days
- Administrations
- 1/ week
Read off the modelled curve, not an even-interval formula
About five half-lives
Where these numbers come from
- AWARD-11 (Frías JP et al., Diabetes Care 2021;44:765)Once-weekly dulaglutide 3.0 mg and 4.5 mg compared with 1.5 mg over 52 weeks in adults with type-2 diabetes.