Head-to-head
Semaglutide vs Liraglutide
Side by side from the same data: half-life, evidence tier, research amounts, common schedule, and every decay curve on one chart.
How they differ
A plain-language read of what actually sets them apart. Reference only, not medical advice.
Both copy the same gut-hormone signal (GLP-1) and come from the same maker, but liraglutide is a daily shot and semaglutide a weekly one. The difference is how long each lasts: about half a day for liraglutide versus about a week for semaglutide. Both have been tested in people in their own weight trials (SCALE and STEP), and both are licensed medicines.
Side by side
Every figure is drawn from this site's own compound data — the same numbers on each compound's page.
| Measure | Semaglutide | Liraglutide |
|---|---|---|
| Category | Metabolic | Metabolic |
| Evidence | A · Tested in people | A · Tested in people |
| Route | Subcutaneous | Subcutaneous |
| Half-life | 168 h | 13 h |
| Typical vial | 3 / 5 / 10 mg | 6 mg |
| Research amount | 0.25–2.4 mg | 0.6–3 mg |
| Common schedule | Once a week | Every day |
| Cycle / break | Titrated | — |
| Studied for | Metabolism and weight | Metabolism and weight |
These amounts and schedules are figures discussed in research and community reports, shared for learning — not a recommendation and not medical advice. A step-by-step dosing schedule exists only where a human trial backs it; the evidence tier tells you which.
Decay curves, overlaid
Every compound on one chart — something the single-compound pages cannot show.
Each line is scaled to that compound's own first dose, so the chart shows how each one builds up over time — not how the compounds' doses compare to one another, which these different molecules share no common unit for.