Head-to-head
PT-141 vs Melanotan-2 (MT-2)
Side by side from the same data: half-life, evidence tier, research amounts, common schedule, and every decay curve on one chart.
How they differ
A plain-language read of what actually sets them apart. Reference only, not medical advice.
Both switch on the same melanocortin receptors, which is why they share effects like nausea and flushing. PT-141 (bremelanotide) sticks to one of those receptors and is a licensed medicine used now and then. Melanotan-2 hits them more broadly and is better known for tanning; its only human dosing came from a tiny three-person 1996 study, so its top tested-in-people grade is shaky. Both are short-acting, gone within a few hours.
Side by side
Every figure is drawn from this site's own compound data — the same numbers on each compound's page.
| Measure | PT-141 | Melanotan-2 (MT-2) |
|---|---|---|
| Category | Sexual and reproductive health | Sexual and reproductive health |
| Evidence | A · Tested in people | A · Tested in people |
| Route | Subcutaneous | Subcutaneous |
| Half-life | 2.7 h | 1.5 h |
| Typical vial | 10 mg | 10 mg |
| Research amount | 0.5–2 mg | 0.7–2.1 mg |
| Common schedule | Once a week | 5 days on, 2 off |
| Cycle / break | — | loading then maintenance / as desired |
| Studied for | Sexual and reproductive health | Sexual and reproductive health |
These amounts and schedules are figures discussed in research and community reports, shared for learning — not a recommendation and not medical advice. A step-by-step dosing schedule exists only where a human trial backs it; the evidence tier tells you which.
Decay curves, overlaid
Every compound on one chart — something the single-compound pages cannot show.
Each line is scaled to that compound's own first dose, so the chart shows how each one builds up over time — not how the compounds' doses compare to one another, which these different molecules share no common unit for.
How they combine
Where two of these have a documented pairing in this reference.
Educational reference on commonly-discussed combinations, not medical advice. Combining compounds can change how each behaves — read this as a prompt to research, not a clearance.
- PT-141 + Melanotan-2 (MT-2)Both are melanocortin-receptor agonists, so combining them intensifies shared effects such as nausea and flushing.Use caution